sodium polystyrene sulfonate dosage. The infants had no clinically noticeable side effects. Do not use in larger or smaller amounts or for longer than recommended. Sodium Polystyrene Sulfonate is contraindicated in the following conditions: patients with hypokalemia, patients with a history of hypersensitivity to polystyrene sulfonate resins, obstructive bowel disease, neonates with reduced gut motility (postoperatively or drug induced) and oral administration in neonates. RESONIUM CALCIUM (calcium polystyrene sulfonate) is a cation exchange resin prepared in the calcium phase. In vitro binding studies showed that Sodium Polystyrene Sulfonate Powder, for Suspension bound significantly to the following tested drugs - warfarin, metoprolol, phenytoin, furosemide, amlodipine and amoxicillin. -This drug should be given as a suspension in water or syrup (not … What is sodium polystyrene sulfonate (Kalexate, Kayexalate, Kionex)? While using as an oral suspension, it should not be heated or should not be used along with heated foods or liquids, because this may cause a decrease in the effectiveness of this drug. Do not use potassium supplements, calcium supplements, or salt substitutes while you are taking sodium polystyrene sulfonate, unless your doctor has told you to. The following adverse reactions have been identified during post-approval use of Sodium Polystyrene Sulfonate Powder, for Suspension. Hyperkalemia often has no symptoms that you will notice until your potassium levels are very low. You may need to hold in the enema for up to several hours. Do not use two doses at one time. NDC 42806-013-96. The average total daily adult dose of sodium polystyrene sulfonate is 15 g to 60 g, administered as a 15-g dose (four level teaspoons), one to four times daily. Everyday Health is among the federally registered trademarks of Everyday Health, Inc. and may not be used by third parties without explicit permission. Do not use the medicine orally or rectally in a baby who has slow digestion caused by surgery or by using other medicines. Select one or more newsletters to continue. Binding of Sodium Polystyrene Sulfonate Powder, for Suspension to other oral medications could cause decreased gastrointestinal absorption and loss of efficacy when taken close to the time Sodium Polystyrene Sulfonate Powder, for Suspension is administered. Sodium polystyrene sulfonate is usually taken or used one to four times a day. Assess abdomen and note character and frequency of stools. Both sodium zirconium cyclosilicate and sodium polystyrene sulfonate belong to a drug class known as potassium binders. 2 Qualitative and Quantitative Composition. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem fo… This sodium is swapped for potassium in the body, particularly in the large intestine. Ensure an adequate volume of cleansing solution (up to 2 liters) is utilized. The majority of these cases reported the concomitant use of sorbitol. Polystyrene sulfonate is used to treat high levels of potassium in the blood, also called hyperkalemia. A dosage of 0.5 to 1 g sodium polystyrene sulfonate powder per 100 mL formula/breast milk appears to be a common initial dosage range used. The drug is a cream to light brown finely ground, powdered form of sodium polystyrene sulfonate, a cation-exchange resin prepared in the sodium phase with an in vitro exchange capacity of approximately 3.1 mEq (in vivo approximately 1 mEq) of potassium per gram. Brand names for sodium polystyrene sulfonate … Administer Sodium Polystyrene Sulfonate Powder, for Suspension at least 3 hours before or 3 hours after other oral medications. Sodium polystyrene sulfonate is usually taken or used one to four times a day. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Follow all directions on your prescription label and read all medication guides or instruction sheets. If you or your child are not able to swallow the liquid, the medicine can be given in the stomach using a special tube. The enema will be inserted slowly while you are lying down. Sodium Polystyrene Sulfonate(Kayexalate) generic is a potassium-removing resin, prescribed for hyperkalemia (without ECG changes). Pharmacology, adverse reactions, warnings and side effects. Keep using this medicine even if you feel fine. Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Describes the best time to take the drug and precautions if any that should be followed. sodium polystyrene sulfonate … Take or use sodium polystyrene sulfonate at around the same time(s) every day. The sodium polystyrene sulfonate enema is usually followed with a second cleansing enema. Administer as a warm (body temperature) emulsion in 100 mL of aqueous vehicle and flush with 50 to 100 ml of fluid. Sodium Polystyrene Sulfonate Powder, for Suspension is not absorbed systemically following oral or rectal administration and maternal use is not expected to result in fetal risk. To give this medicine orally: Mix the sodium polystyrene sulfonate powder with water, or with honey or jam to make it taste better. Sodium polystyrene sulfonate is used to treat high levels of potassium in the blood, also called hyperkalemia. Sodium Polystyrene Sulfonate Powder, for Suspension is not absorbed systemically by the mother, so breastfeeding is not expected to result in risk to the infant. Decreased absorption of lithium and thyroxine have also been reported with co-administration of Sodium Polystyrene Sulfonate Powder, for Suspension. Do not heat Sodium Polystyrene Sulfonate Powder, for Suspension as it could alter the exchange properties of the resin. Concurrent low-sodium diet may be ordered for patients with HF In patients receiving concurrent digoxin, assess for symptoms of digoxin toxicity (anorexia, nausea, vomiting, visual disturbances, arrhythmias). Last updated on Nov 1, 2019. Sodium Polystyrene Sulfonate Dosage & Precautions Before using sodium polystyrene sulfonate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Dosage is individualized and depends on daily assessment of total body potassium. sodium polystyrene sulfonate + aluminum hydroxide avoid combo w/ oral sodium polystyrene sulfonate or use alternative; interaction less likely w/ rectal admin. Comments: -A 15 g dose is equivalent to approximately 4 level teaspoons. Rectal. Call your doctor for medical advice about side effects. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Menu. Administer other oral medications at least 3 hours before or 3 hours after Sodium Polystyrene Sulfonate Powder, for Suspension. Resonium A contains 99.93% sodium polystyrene sulfonate as a finely ground powder. Resonium A (sodium polystyrene sulfonate). Oral The average total daily adult dose of Sodium Polystyrene Sulfonate is 15 g to 60 g, administered as a 15-g dose (four level teaspoons), one to four times daily. Overdosage may result in electrolyte disturbances including hypokalemia, hypocalcemia, and hypomagnesemia. Rx Only. Discontinue sodium polystyrene sulfonate … The rectal enema form of this medicine is usually given by a healthcare professional. The in vivo efficiency of sodium-potassium exchange resins is approximately 33 percent; hence, about one third of the resin's actual sodium content is delivered to the body. Use the medicine exactly as directed. Do not give this medicine orally (by mouth) to a newborn baby. (sodium polystyrene sulfonate) POWDER 1 NAME OF THE MEDICINE Resonium A (sodium polystyrene sulfonate). Resonium A contains sodium polystyrene sulfonate which contains sodium atoms. Do not use potassium supplements , calcium supplements , or salt substitutes while you are taking sodium polystyrene sulfonate, unless your doctor has told you to. Sodium polystyrene sulfonate may also be used for purposes not listed in this medication guide. how long does it take to start workingk? The practical exchange ratio is 1 mEq K per 1 gram of resin. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to estimate their frequency reliably or establish a causal relationship to drug exposure. The efficiency of this process is limited and unpredictably variable. Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. In both children and neonates, excessive dosage or inadequate dilution could result in impaction of the resin. Administer with patient in an upright position [see Warnings and Precautions (5.4)]. Sodium polystyrene sulfonate is used to treat high levels of potassium in the blood, also called hyperkalemia. a weak immune system caused using certain medicine; severe constipation or other bowel problems; kidney disease (or if you are on dialysis); an electrolyte imbalance (such as low levels of potassium, calcium, or magnesium in your blood); a bowel disorder, or surgery on your intestines; severe constipation, severe stomach pain, bloating; confusion, thinking problems, feeling irritable.